الوصف

 

Specification	**0mg/2ml
Package	*0amps/tray/box

â’ˆPharmacology

Ascorbic acid, a water-soluble vitamin, is essential for formation of collagen and intercellular material, and therefore necessary for the development of cartilage, bone, teeth and for the healing of wounds. It is also essential for the conversion from folic acid to folinic acid, facilitates iron absorption from the gastro-intestinal tract and influences haemoglobin formation and erythrocyte maturation.

â’‰Indications

The prevention and treatment of scurvy, or other conditions requiring vitamin C supplementation, where the deficiency is acute or oral administration is difficult.

â’ŠDosage

Route of Administration: Parenteral

Adults

0.5 to 1g daily for scurvy, **0 to **0mg daily for preventative therapy.

Children

**0 to **0mg daily for curative purposes, or *0mg daily for protective treatment.

Elderly

No special dosage requirements have been suggested.

â’‹Contraindications

Hyperoxaluria

â’ŒSpecial Precautions

Ascorbic acid should be given with care to patients with underlying renal due to the risk of formation of renal oxalate calculi. Tolerance may be induced in patients taking high doses.

Large doses of Ascorbic Acid have resulted in haemolysis in patients with glucose **-phosphate dehydrogenase(G6PD)deficiency.

⒍Undesirable effects

Large doses may cause gastrointestinal disorders including diarrhoea. Large doses may also result in hyperoxaluria and renal oxalate calculi may form if the urine becomes acidic. Doses of **0mg or more daily have a diuretic action. Induced tolerance with prolonged use of large doses can result in symptoms of deficiency when intake is reduced to normal.

â’ŽDrug Interactions

Drugs which induce tissue desaturation of ascorbic acid include aspirin, nicotine from cigarettes, alcohol, several appetite suppressants, iron phenytoin, some anti-convulsant drugs, the oestrogen component of oral contraceptives and tetracycline. Large doses of ascorbic acid may cause the urine to become acidic

Causing unexpected renal tubular reabsorption of acidic drugs, thus producing an exaggerated response. Conversely basic drugs may exhibit decreased reabsorption resulting in a decreased therapeutic effect. Large doses may reduce the response to oral anticoagulants.

It has been reported that concurrent administration of ascorbic acid and fluphenazine has resulted in decreased fluphenazine plasma concentrations.

Ascorbic acid is a strong reducing agent and interferes with numerous laboratory tests based on oxidation-reduction reactions. Specialised references should be consulted for specific information on laboratory test interferences caused by ascorbic acid.

Ascorbic acid given in addition to desferrioxamine in patients with iron overload to achieve better iron excretion may worsen iron toxicity, particularly to the heart, early on in the treatment when there is excessive tissue iron. Therefore it is recommended that in patients with normal cardiac function ascorbic acid should not be given for the first month after starting desferrioxamine. Ascorbic acid should not be given in conjunction with desferrioxamine in patients with cardiac dysfunction.

Aspirin can reduce the absorption of ascorbic acid by approximately a third and decreases urinary excretion by about half. The clinical importance of this is uncertain.

Patients with kidney failure given aluminium antacids and oral citrate can develop a potentially fatal encephalopathy due to marked rise in blood aluminium levels. There is evidence that vitamin C may interact similarly.

Oral contraceptives lower serum levels of ascorbic acid.

 

⒏Storage and shelf life

Do not store above 25℃

Shelf life: 2years.

 

ARTEMETHER INJECTION

DESCRIPTION:

A colorless or yellowish clear oily solution

PHARMACOLOGY AND TOXICOLOGY:

Animal pharmacodynamics showed that the drug is a strong schizonticide. Parasitemia clearance occurs rapidly with stable efficacy after administration. It is also effective against chloroquine-resistant P. falciparum malaria. Acute toxicity studies on animals showed that the LD*0 of Artemether in mice of a single i.g. administration is **5mg/kg and a single i.m. injection is **6mg/kg; in rats, the LD of a single i.m. injection is **7mg/kg. This proves the toxicity of Artemether is quite low.

 

بلد:	China
نموذج رقم:	S11115D341
سعر فوب:	0.1 ~ 1 / Box ( Negotiable ) (قابل للتفاوض) أحصل على آخر سعر
الموقع:	-
سعر الحد الأدنى للطلب:	0.1 per Box
الحد الأدني للطلب:	1 Box
تفاصيل التغليف:	10amps/tray/box
موعد التسليم:	20 days for ready goods, 35 days for OEM
القدرة على التوريد:	10000 Box per Month
نوع الدفع:	Other, PayPal, Western Union, D/P, L/C, T/T
مجموعة المنتج :	Whitening Glutathione