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What is Omega-3 and what is it good for? Omega-3 is an essential fatty acid (EFA), also known as a polyunsaturated fatty acid (PUFA). It is derived from both animal and plant sources, although Omega-3 from fish oil is the most common supplemental form. Fatty acids form the main useful fraction of fats and oils and are necessary for overall health. Because your body cannot manufacture essential fatty acids, you must get them from food or supplemental sources. Plant sources such as Flax Oil contain the parent Omega-3 fatty acid called Alpha-linolenic acid (ALA). The human body normally converts ALA to the longer chain fatty acids EPA and DHA, which are used for prostaglandin formation and other cellular needs. Fish Oil contains the desired Omega-3 fatty acids in their more useful EPA and DHA forms. ALA requires enzymatic conversion to generate EPA and DHA.