الوصف

Chenodeoxycholic acid is synthesized in the liver from cholesterol via several enzymatic steps. CDCA has been used as medical therapy to dissolve gallstones. Medical therapy with oral bile acids has been used in patients who have small cholesterol stones, and for patients with larger cholesterol gallstones who are unable or reluctant to have surgery. CDCA treatment can cause diarrhea, mild reversible hepatic injury, and a small increase in the plasma cholesterol level. CDCA can be used in the treatment of cerebrotendineous xanthomatosis.