Emtricitabine

الوصف

Relative molecular mass. **7.2 Chemical name. *-amino**-fluoro**-[(2R,5S)**-(hydroxymethyl)*1,*-oxathiolan**-yl]pyrimidin*2(1H)-one; *-fluoro**-[(2R,5S)**- (hydroxymethyl)*1,*-oxathiolan**-yl]cytosine; (-)*2',3'-dideoxy**-fluoro*3'-thiacytidine; CAS Reg. N° **********0. Description. White to almost white, crystalline powder. Solubility. Freely soluble in methanol R and water R, practically insoluble in dichloromethane R. Category. Antiretroviral (Nucleoside Reverse Transcriptase Inhibitor). Storage. Emtricitabine should be kept in a tightly closed container. Additional information. Emtricitabine may exhibit polymorphism. Requirements Definition. Emtricitabine contains not less than *9.0% and not more than **1.0% of emtricitabine (C8 H*0FN3 O3 S), calculated with reference to the dried substance. Manufacture. The production method is validated to ensure that the substance, if tested, would comply with a limit of not more than 0.3% for the (2S,5R)-enantiomer using a suitable chiral chromatographic method. Relative molecular mass. **7.2 Chemical name. *-amino**-fluoro**-[(2R,5S)**-(hydroxymethyl)*1,*-oxathiolan**-yl]pyrimidin*2(1H)-one; *-fluoro**-[(2R,5S)**- (hydroxymethyl)*1,*-oxathiolan**-yl]cytosine; (-)*2',3'-dideoxy**-fluoro*3'-thiacytidine; CAS Reg. N° **********0. Description. White to almost white, crystalline powder. Solubility. Freely soluble in methanol R and water R, practically insoluble in dichloromethane R. Category. Antiretroviral (Nucleoside Reverse Transcriptase Inhibitor). Storage. Emtricitabine should be kept in a tightly closed container. Additional information. Emtricitabine may exhibit polymorphism. Requirements Definition. Emtricitabine contains not less than *9.0% and not more than **1.0% of emtricitabine (C8 H*0FN3 O3 S), calculated with reference to the dried substance. Manufacture. The production method is validated to ensure that the substance, if tested, would comply with a limit of not more than 0.3% for the (2S,5R)-enantiomer using a suitable chiral chromatographic method. Relative molecular mass. **7.2 Chemical name. *-amino**-fluoro**-[(2R,5S)**-(hydroxymethyl)*1,*-oxathiolan**-yl]pyrimidin*2(1H)-one; *-fluoro**-[(2R,5S)**- (hydroxymethyl)*1,*-oxathiolan**-yl]cytosine; (-)*2',3'-dideoxy**-fluoro*3'-thiacytidine; CAS Reg. N° **********0. Description. White to almost white, crystalline powder. Solubility. Freely soluble in methanol R and water R, practically insoluble in dichloromethane R.Relative molecular mass. **7.2 Chemical name. *-amino**-fluoro**-[(2R,5S)**-(hydroxymethyl)*1,*-oxathiolan**-yl]pyrimidin*2(1H)-one; *-fluoro**-[(2R,5S)**- (hydroxymethyl)*1,*-oxathiolan**-yl]cytosine; (-)*2',3'-dideoxy**-fluoro*3'-thiacytidine; CAS Reg. N° **********0. Description. White to almost white, crystalline powder. Solubility. Freely soluble in methanol R and water R, practically insoluble in dichloromethane R.Relative molecular mass. **7.2