الوصف

1, 4 - butyrolactone, also called gamma butyrolactone, 4 - hydroxy butyric acid lactone. Is a colorless, oily liquid, can be immiscible with water, but soluble in methanol, ethanol, acetone, ether and benzene. Can with water vapor volatilization and decomposition in hot alkali solution, fragrant smell.

Molecular formula: C4H6O2

Molecular structure: carbonyl C and O atoms to sp2 hybrid orbitals form sigma bond. Other C and O atoms to sp3 hybridized orbital forming sigma bond.

The relative molecular weight € *6.*9

Relative density 1.***3 density € €Â (*5/4 ƒ)

Melting point (ƒ) € €Â *3.*3

The boiling point (ƒ) € **4

The refractive index of *5 ƒ € 1.***8

World electric constant (*0 ƒ) *9

Dipole moment (*5 ƒ benzene) : *3.*4

Critical temperature: **6 ƒ

Critical pressure: 3.4 mPa.

Viscosity: 1.7 mPa s *5 degrees C.

Tension: *2.3 mN/m. *5 degrees C.

Flash: *8.3 (open loop).

Evaporation heat (**4 ƒ) (kj/mol) : *2.3

In a neutral medium stability, reversibility in hot alkali hydrolysis, ph back to neutral and generate lactone, hydrolysis in acidic medium is slower.

"Dissolve situation"

Miscibility with water, but soluble in methanol, ethanol, ethyl ether, acetone, benzene, carbon tetrachloride.

Use note: for combustible liquid, avoid direct contact with the fire.

Toxicity: low toxicity. In mice by oral LD*0 = **5 mg/kg. Are irritating to the skin.

The derivatives of 1, 4 - butyrolactone is numerous, can be the product of the reaction generated by a variety of different and wide range of USES, specific as follows: [1]

Generate gamma hydroxy butyric acid hydrolysis, resin can be used as special plasticizer, pharmaceutical intermediates;

For the oxidation of ChengDing diacid; Reduction to generate 4 - hydroxy butyl aldehyde, 1, 4 - butanediol then restore formation;

Generate alpha, condensation acetal in alpha hydroxy ketone;

Can react with CH3NH2, generate N - methyl - 2 - pyrrolidone;

Can generate tetrahydrofuran;

Can react with SO3 ChengDing lactone - alpha - sulfonic acid;

Can react with NaCN generated 2 - piperidine ketone;

Glutaric acid can react with CO formation;

Can be generated by reaction with NaOH 4, 4 - oxygen generation of succinic acid;

Can react with Na2S generate sulfur brace succinic acid;

Can react with NA2SO3 to generate gamma sulfo sodium butyrate.

1, 4 - butyrolactone is widely used as spices and pharmaceutical intermediates. As a kind of high boiling point solvents, strong solubility, performance and good stability, the use of safe. As a proton type strong solvent, can dissolve the most low molecular polymer and polymer, can be used as a battery electrolyte, in lieu of the corrosive acid. In the polymerization reaction can participate as a carrier and polymerization. Can be used for pyrrolidone, butyric acid, succinic acid, to paint potions, in medicine, spices and other fine chemicals synthesis application is very wide. Also commonly used as solvent, resin is high/low toxicity safety and environmentally friendly solvent. In the field of polyurethane, used for polyurethane viscosity modifier (reactive diluent), and curing agent of polyurethane (pu) and amino coatings system.