الوصف

Freeze drying can occur naturally, but it was not until the end of the *9th century that it was discovered that the process could be accelerated by the application of vacuum. In freeze drying, liquid is removed from a substance directly from the solid (frozen) state, under vacuum, to the vapor state. This process is known as sublimation, and a freeze drying cycle has stages as follows:
 

Preparation (pretreatment): such as production of Food class, API, formulations, sterilization, container preparation, filling, half stoppering of formulated drug; program selection
 
lFreezing (or pre-freezing): freeze products to solid state;
lPrimary drying(sublimation): this is the part of the process when the frozen water is converted from ice directly to vapor;
lSecondary drying(desorption drying): this is the part of the process where the remaining small proportion of bound liquid is removed;
lSealing and packaging: dried products are sealed and packaging under vacuum or inert gas.
 
Freeze drying [lyophilization] has the advantages of preventing protein from degeneration and preserving the efficacy of the dried material, with long expiry periods. Historically lyophilization provides a very short time to providing a stabile product and that is what prompts its use in the pharmaceutical industry. At present, lyophilizers are used for biological-products, pharmaceuticals and foods and many other products. To supply the rising demand for lyophilizers in the in these industries was formed by us for the manufacture of freeze dryers according to the current codes and standards.


LAM*0.5based on standard design, Specific standard as follows: