Sell Tanshinone IIA

Description

•SPECIFICATIONS Offered as 5 mg (sc******2) and *5 mg (sc******2A) sizes CAS Number: *******9 Molecular Weight: **4.3 Molecular Formula: C*9H*8O3 Purity: *8% Physical Appearance: Orange solid Solubility: Soluble in DMSO (*5 mg/mL) and ethanol (5 mg/mL) SMILES: CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C •DESCRIPTION Tanshinone IIA is derived from phenanthrene-quinone, which can be isolated from Salvia miltiorrhiza BUNGE. The compound can promote anti-inflammatory, anti-oxidative, and cytotoxic activity, and well as induce apoptosis. Tanshinone IIA has been shown to decrease levels of iNOS and inhibit synthesis of TNF-α, nitric oxide, and IL*1β. Research has indicated that Tanshinone IIA can inhibit the migration of human aortic smooth muscle cells (HASMC) and AP*1 DNA-binding. NF-α-stimulated brain microvascular endothelial cells (BMVECs) studies have supporting evidence that Tanshinone IIA can inhibit the activation of nuclear factor-κ B (NF-κB) and ROS generation. •STORAGE Store, as supplied, at **0°C for up to 1 year. Store solutions at **0°C for up to 3 months. •FOR RESEARCH USE ONLY The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.