Description

Product name:Nigericin CAS:*********3 Molecular Formula:C*0H*8O*1 Molecular Weight:**4.****2 Product description:Nigericin is an antibiotic derived from Streptomyces hygroscopicus. Its isolation was described in the ***0s[1] but in ***8 the structure could be elucidated by X-ray crystallography.[2] The structure and properties of nigericin are similar to the antibiotic monensin. Commercially it is obtained as a byproduct, or contaminant, at the fermentation of Geldanamycin. It is also called Polyetherin A, Azalomycin M, Helixin C, Antibiotic K**8, Antibiotic X***4. Nigericin acts as an H , K , Pb2 ionophore. Most commonly it is an antiporter of H and K . In the past nigericin was used as an antibiotic active against gram positive bacteria. It inhibits the Golgi functions in Eukaryotic cells. Nigericin exhibits anti-HIV activity.