Description
Product Name: Naringin
Effectiveness: Cardiovascular health / Antisepsis and
anti-inflammation / Antivirus / Digestive system
1. Sources and habitation
Naringin is the major flavonoid glycoside in grapefruit and gives
grapefruit juice its bitter taste. It is metabolized to the
flavanone naringenin in humans. Both naringenin and hesperetin,
which are the aglycones of naringin and hesperidin, occur naturally
in citrus fruits.
2. Descriptions and Specifications of Product
Content Specifications: *8% Naringin by HPLC
Naringin
Molecular Formula: C*7H*2O*4
Molecular Mass: **0.*4
CAS No: *********2
Constitutional Formula:
3. Indications and Uses
Naringin exerts a variety of pharmacological effects such as
antioxidant activity, blood lipid lowering, anticancer activity,
and inhibition of selected drug-metabolizing cytochrome P**0
enzymes, including CYP3A4 and CYP1A2, which may result in drug-drug
interactions in vivo. Ingestion of naringin and related flavonoids
can also affect the intestinal absorption of certain drugs, leading
to either an increase or decrease in circulating drug levels. To
avoid interference with drug absorption and metabolism, the
consumption of citrus (esp. Grapefruit) and other juices with
medications is contraindicated.
Naringin, followed by rutin, was the most potent flavonoid
inhibitor of VEGF release, which causes angiogenesis, out of *1
flavonoids. When Naringin is treated with potassium hydroxide or
another strong base, and then catalytically hydrogenated, it
becomes a naringin dihydrochalcone, a compound roughly *******0
times sweeter than sugar at threshold concentrations
