Description

*-Fluoroorotic Acid Molecular Formula: C5H3FN2O4 . CAS Number: *******7 Description: *-Fluoroorotic Acid (*-fluorouracil**-carboxylic acid monohydrate; *-FOA) is widely used in yeast molecular genetics. *-FOA is toxic to yeast cells with a functioning URA3 gene encoding orotidine5&#**9;-monophosphate decarboxylase (OMP decarboxylase). *-FOA is therefore especially useful for the selection and identification of mutant yeast strains. 5&#**9;-FOA&#**9;s use in the yeast *-hybrid system allows the construction of activation domain hybrid libraries to identify protein-protein interactions (1). Quality Control Purity: >*8% or > *9% (by HPLC). Storage Store at **0 oC in the dark.