Description
Physiological effect:
Choline and its metabolites are needed for three main physiological
purposes: structural integrity and signaling roles for cell
membranes, cholinergic neurotransmission (acetylcholine synthesis),
and as a major source for methyl groups via its metabolite,
trimethylglycine (betaine) that participates in the
S-adenosylmethionine synthesis pathways.
Apply:
1ã€Contribute to treatment of Alzheimer\'s disease
2ã€Treatment of nervous system diseases such as Parkinson\'s
disease and tardive dyskinesia helpful
3ã€Control fat and cholesterol savings
4ã€Promote liver function, help the body eliminate toxins
organization
5ã€Help send a signal to stimulate the nerve, prevent old age
memory loss.
Deficiency:
Lack of long-term intake of dietary choline may include the main
findings of the liver, kidney, pancreas disease, memory disorders
and growth failure.
1ã€the liver changes: most of the animals, the lack of choline can
cause liver dysfunction, a large number of liver lipid (mainly
triglyceride) accumulation and eventually filled the entire liver
cells.
2ã€kidney changes: lack also harmful to the kidneys shrink
cholinergic function.
3ã€induced cancer: lack of choline caused by genetic damage caused
by carcinogenic process first, and then some can form tumor cell
survival and proliferation of variations.
4ã€Low-choline diet-related symptoms:infertility, growth
retardation, bone abnormalities, blood disorder and hypertension
were also reported.