Description
Macleaya
cordataExtractsProfile
Product
Specification:*0%Total
alkaloids（HPLC）[*6%~*4%Sanguinarinesulfateã€*8%~*2%
Chelerythrine sulfate]
Latin
Name:Macleaya Cordata
(Willd.)R.Br.
Botanical
Source: Fruit
What
isMacleaya
cordataExtracts?
Macleaya cordata, common name plume poppy and
bocconia, belongs to the family Papaveraceae, is a herb native to
herb of China and Japan. It is a perennial plant, with deep lobed
leaves and dusty clouds of tiny bossoms at the tips of erect stems,
most often a white color. It is widely cultivated as an ornamental
plant for its plumelike panicles of creamy white
flowers.
Macleaya cordata is a poisonous plant.
Macleaya cordata (Willd.)R.Br is a bloodroot which owns thousand
year history of medicinal usage in China. Macleaya cordata extract
contains sanguinaine and chelerythrine, which have fungicidal and
insecticidal activity. Sanguinarine (pseudochelerythrine) is a
potent inhibitor of NF-kappaB activation, IkappaBalpha
phosphorylation, and degradation.Macleaya cordata contains several
alkaloids including sanguinarine, chelerythrine, protopine, and
allocryptopine.
What are Health Benefits?
Macleaya cordata Extract has the function of
detumescence, detoxification and pesticide. It can be used in the
treatment of furuncle, abscess, malignant boil, ulcer, scald and
intractable tinea, etc. The product is virose and can not be taken
orally. Macleaya cordata extract mainly constains with sanguinarine
and chelerythrine. It was been show to be reversible inhibitors of
the enzymatic hydrolysis of acetylthiocholine. It was reported that
a study was made of a possible inhibitory action on the enzymatic
hydrolysis of acetylthiocholine by human erythrocyte
acetylcholinesterase of principal alkaloids isolated from
Chelidonium majusL. and Macleaya cordata and microcarpa,and of
drugs Ukrain and Sanguirythrine. Among all examined agents
berberine, sanguinarine and Sanguirythrine were the strongest
inhibitors of this reaction.Judging from the data obtained,
sanguinarine and chelerythrine exert similar inhibitory effects on
the reaction of enzymatic hydrolysis of acetylthiocholine.
New anticancer drugs have been exploited with
germs of Macleaya Cordata as the raw material by extraction and
separation of alkaloid. Such as for treating Prostate cancer,
Sanguinarine causes cell cycle blockade and apoptosis of human
prostate carcinoma cells via modulation of cyclin kinase
inhibitor-cyclin-cyclin-dependent kinase machinery. Several studies
have shown that plant-derived alkaloids possess remarkable
anticancer effects. Sanguinarine, an alkaloid derived from the
bloodroot plant Sanguinaria canadensis, has been shown to possess
antimicrobial, anti-inflammatory, and antioxidant properties.
Previously, we have shown that sanguinarine possesses strong
antiproliferative and proapoptotic properties against human
epidermoid carcinoma A**1 cells and immortalized human HaCaT
keratinocytes. These results suggest that sanguinarine may be
developed as an agent for the management of prostate cancer.
The Macleaya cordata Extract used in dietary
supplements is derived from the fruits of the plant Macleaya
cordata.
Producing
Process:
Plant==>Raw
Material==>Extraction==>Filtration==>Cool Down==>Spray
Dry(much methods to dry) Into Power==>Sifter
Powder==>Packing
Packing
Detail:
*5KG/fiber
drum in net weight, *8KG /fiber drum in gross
weight.
*5KG :Inner packing: double-layer aluminum foil
bag
Outer packing: Fiberboard
drum
The sample:
packed in Foil paper, and two
plastic-bags inside.
*0KG: packed in Carton, and two
plastic-bags inside.
