Description
Biological
importance
This acid is an important factor in plant metabolism. It is also an
antioxidant and an inhibitor of the tumor promoting activity of
phorbol esters; at concentrations as high as **0 µg/L, does not
inhibit the *-lipoxygenase activity of ionophore-stimulated human
polymorphonuclear leukocytes.
Chlorogenic acid and caffeic acid are antioxidants in
vitro and might therefore contribute to the prevention of Type 2
Diabetes Mellitus and cardiovascular disease.
Chlorogenic acid, an ester of caffeic acid and
quinic acid, is a major phenolic compound in coffee; daily intake
in coffee drinkers is 0.5–1 g. Chlorogenic acid and caffeic acid
are antioxidants in vitro and might therefore contribute to the
prevention of cardiovascular disease.
Chlorogenic acid has been proven in animal
studies in vitro to inhibit the hydrolysis of the
glucose**-phosphate enzyme in an irreversible fashion. This
mechanism allows chlorogenic acid to reduce hepatic glycogenolysis
(transformation of glycogen into glucose) and to reduce the
absorption of new glucose. In addition, in vivo studies on animal
subjects have demonstrated that the administration of chlorogenic
acid lessens the hyperglycemic peak resulting from the
glycogenolysis brought about by the administering of glucagen, a
hyperglycemiant hormone. The studies also confirmed a reduction in
blood glucose levels and an increase in the intrahepatic
concentrations of glucose**-phosphate and of glycogen.
Chlorogenic acid can be used as anti-infectious
active ingredient, it has wide anti-virus, anti-bacteria effects,
and has relatively lower toxicity and side-effects. It has obvious
anti-infectious effects, and does not like to lead Anti-microbial
Resistance.
Due
to its obvious anti-infectious effects, it not only can be used in
pharmaceutical field but can be used widely in many other fields
like food, feed additives, cosmetics also.
Chlorogenic Acid—Best ingredients
for cosmetic products
I. Strong Anti-oxidant
ability
II.**0% water soluble
III.Very stable at normal
temperature
IV.Pure white
V. No hypersusceptibility
VI.**0% natural
VII.**0% safe for Honeysuckle
Flower is drink as a tea for more than ***0 years in
China.
