Description

Botanical source: Magnolia officinalis Rehd.et Wils. Biogenic origin: Wild in central and southern China A compound found in magnolia species holds exciting promise in the management of anxiety, cancer, and other challenging conditions. Honokiol is a bi-phenolic compound with the formula C*8H*8O2 and a relatively small molecular weight of **6 grams/mole. This molecule is found in several species of the genus magnolia including M. officinalis, obovata, and grandifolia. It is an isomer of another compound also found in magnolia materials called magnolol, which has ***0 times the antioxidant potential of vitamin E. The dried bark of M. officinalis usually has about **5% hanokiol and ***0% magnolol. Magnolia Species and Traditional Use While magnolia species have been incorporated in traditional healing systems throughout the world, the barks of Chinese M. officinalis and Japanese M. obuvata have become quite popular due to their verified levels of phytochemicals like honokiol. The bark of M. officinale (houpa) is often sought for incorporation in traditional Chinese formulas addressing “chi stagnation”, asthma, anxiety, cancer, and digestive disorders. China produces well over **0 tons of magnolia bark a year. With its popularity comes the concern of over-harvesting since the tree is killed during bark procurement. A positive side to this is that the honokiol molecule is not very complex and is easily synthesized through organic chemistry methods. Pharmokinetics Honokiol appears to be non toxic, easily absorbed, and systematically available. This is important since many promising materials like Epigallocatechin Gallate (EGCG) are not absorbed well in the digestive tract. Honokiol also avoids immediate clearing by the liver (first pass effect) and crosses blood barriers that often exclude other compounds.Honokiol has a significant, long-lasting central muscle relaxation, inhibition of the central nervous system, anti-inflammatory, antibacterial, disease of the original microbial, anti-ulcer, anti-oxidation, anti-tumor, morphine withdrawal response, inhibit platelet aggregation and other pharmacological effects for the treatment of acute enteritis. bacterial or amoebic dysentery. chronic gastritis. Among them, the antibacterial effect of magnolol on the Gram-positive bacteria, acid-resistant bacteria, filamentous fungi have significant antimicrobial activity, a more significant antibacterial effect on Streptococcus mutans, the strongest inhibitory effect on Staphylococcus aureus. Clinically for the elimination of the chest and abdomen full of nausea, sedation central nervous system, athletes, muscle relaxants, anti-fungal, anti-ulcer drugs Eucommia Ulmoides Extract Chlorogenic Acid ***8% Banaba Leaf Extract Crosolic Acid ***8% Privet Leaf Extract Ursolic Acid ****8%,*5% Honeysuckle FlowersExtract Chlorogenic Acid ***9% Bitter Apricot Seed Extract Amygdalin ****8% Flax Seed Extract secoisolariciresinol Diglucoside *0%，*0% Grape Skin Extract Resveratrol *0%**8% Rhubarb Extract Emodin *0%,*8% Ampelopsis Gressedentata Extract Dihydromyricetin *5%,*8% China Bayberry Bark Extract Myricetin *5%**8% Grape Seed Extract OPC 5%**8% Eurycoma Longifolia Extract 4:1,*0:1, **0:1 Shorthorned Epimedium Extract Icariin ****8% Fructus Lycit Extract Lycium Barbarum Polysaccharides *0%**0% Chinese Blueberry Extract OPC(Oligomeric Proantho Cyanidins)*0%,*5%,*0% Magnolia Bark Extract Magnolol *0%,*5%,*8% Honokiol *0%,*5%,*8% Honokiol +Magnolol *0,*8% Lotus Leaf Extract Nuciferine 2% Ginseng Extract Total Ginsenoside Ginseng Root *0%**0% Mulberry Leaf Extract *- Deoxynojirimycin(*-DNJ) 1%**0%,*8% Tomato Extract Lycopene 5%**0% Artemisia Annua Extract Artemisinin *8% Feverfew Extract Parthenolide *5%**8% Polygonum Cuspidatum Extract Resveratro *5%**8% Ligustrum lucidum Ait Extract Oleanic acid *8% Scutellaria Root Extract Baicalin *0%**5% Swertia chirata extract Swertiamarin ****8% Olive leaf extract Hydroxytyrosol ***5% Olive leaf extract Olives bitter glycosides ****0% gotu kola extract Asiaticoside ****0% gotu kola extract Madecassoside ****0% Macleaya cordata Extract sanguinarine ****0% Macleaya cordata Extract cordata Extract ****0% Green tea extract EGCG ****8% Tomato extract Lycopene ***0% Rosehip extract Polypheo l0%,*0% Rosemary extract Rosmarinic acid 2.***8% Peony Extract paeoniflori 5:1,*0:1,*0:1 ****5%