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الشخص الذي يمكن الاتصال به Cathy
No,111 Changguo Road, Zibo, Shandong
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CAS No: **********6
Alternative Name: HTS *****4Chemical Name: *-[*-(*-Pyridinyl)*1H-pyrazol**-yl]-quinoline
M.Wt: **2.*1
Formula: C*7H*2N4
Solubility: Soluble to **0 mM in DMSO
Purity: >*8 %
Storage: Store at RT
Biological Activity:
Selective inhibitor of TGF-β type-I receptor (TGF-β RI, TGFR-I, TβR-I, ALK*5) (IC*0 values are *9, **0 and ***0 nM for TGR-β RI, TGF-β RII and MLK*7K respectively). Inhibits TGF-β-dependent luciferase production in mink lung cells (p3TP lux) and growth in mouse fibroblasts (NIH 3T3) (IC*0 values are *7 and *9 nM respectively). Suppresses invasion of MDA-MB***1 breast cancer cells in a matrigel invasion assay.
