1. Sources and
Habitation
Berberine Hydrochloride
is an alkaloid derived from Chinese goldthread, bark of cork tree
and other plants. It
can be also synthesized in artificial method. It is used as raw
material to make preparations, which
are usually administered the treatment of intestinal infections and
bacillary dysentery. Recently
usage of anti-arrhythmic was found.
2.Descriptions and Specifications of
Product
Plant original: Berberis
vulgaris
Specifications: *8.0%
Berberine hydrochloride Test by HPLC
CAS No:
*******8
3. Indications and Uses
As a traditional medicine
or dietary supplement, berberine has showed some activity against
fungal infections, Candida
albicans, yeast, parasites, and bacterial/viral
infections.Berberine seems to exert synergistic
effects with
fluconazol even in drug-resistant Candida albicans infections.
Some research has been undertaken into possible use
against MRSA infection; Berberine is considered an ineffective
antibiotic.However, when applied in vitro
and in combination with methoxyhydnocarpin, an inhibitor of
multidrug resistance pumps, berberine
inhibits growth
of Staphylococcus aureus; Berberine is a component of some eye drop
formulations. There is some evidence that
it is useful in the treatment of trachoma,and it has been a
standard treatment for leishmaniasis.Berberine
prevents and
supresses proinflammatory cytokines, E-selectin, and genes,
and increases adiponectin expression which partly
explains its versatile health effects. Berberine is a nucleic
acid-binding isoquinolone alkaloid with wide potential
therapeutic properties.
4. Safety
Concerns
Adverse reaction for oral
administration is less nausea, vomiting, rash, fever, disappeared
after drug withdrawal.
5. Dosage
Information
Berberine was
administered orally for 3 days or 1 week at a dosage of 7.5 or *5
mg/kg/day.
Tissue damage scores,
body weight, colon wet weight, and colon wall thickness were
measured, and
myeloperoxidase activity in colon tissue was also examined.
Histological lesions, morphological
damage, and
myeloperoxidase activity were reduced after 1 week of treatment
with berberine at a dosage of *5 mg/kg/day.
The Information had not
been evaluated by the Food and Drug Administration, only for
reference
Jessie Lee | Sales Manager
Peace Fortune Enterprise Limited.
T&F: ***************5
M: ***************7 Skype: jessie*****0
E: jessieATapeacefortune.com
