Colorless or light-yellow liquid,soluble in water, alcohol and other organic solvent
and insoluble in light petroleum
Molecular Formula C4H6O3
Structural Formula
Molecular Weight **2.*9
SPECIFICATION A B
Assay(HPLC) *7% Min *0% Min
Specific Rotation (c=1,EtOH) **4~**6 **5*5
Opecific Purity(e.e%) *9% Mix *9% Mix
MAIN FUNCTION AND PURPOSE S(-)**-Hydroxy-? butyrolactone is an
important intermediate in organic synthesis and an important chiral pool.
It is mainly used in the synthesis of some natural products and some bioactive chiral drugs or antibiotic chiral drugs. For example, it is a key intermediate in synthesis of nerve regulator (R)-GABOB and brain metabolic accelerant S(-)-Oxiracetam. s**-Hydroxy-?butyrolactone can be deoxidized to S(-)**-hydroxy-tetrahydrofurane which is an important intermediate of anti-AIDS drugs. It is also used in the synthesis of S(-)**-hydroxy**-bromobutyric acid which is a potential stabilizer. It can also be used to produce S(-)**-hydroxymethyl-oxazolin which is a new antibiotic drug.