Phenacetin CAS:62-44-2 PHENACETINUM 99%

الوصف

英文名称PHENACETINUM 或PHENACETIN

标准编号WS***5 (B)

含量：*9%

CAS：***4
phenacetin
phenacetin
**2

分子式：C*0H*3NO2

分子量：**9.***8

类别：活性药物成分、解热镇痛活性药物成分。

性状：本品为白色、微闪片状结晶或白色结晶性粉末，无臭，味苦。本品溶于乙醇或氯仿，微溶于沸水

，微溶于水。

质量标准：企业标准或英国药典BP*8版

用途：解热镇痛药，用于治疗发热头痛、神经痛等。

非那西丁又称醋酰氧乙基苯胺。有光泽或鳞片状结晶小叶，无臭，味苦。熔点**4～**7℃。在空气中稳定，极微溶于水，微溶于水，微溶于乙醚，溶于乙醇、氯仿。由硝基氯苯经醚化、还原和乙酰化反应制得。用作乙酰苯胺解热镇痛药。适用于发热、头痛、神经痛，并与其他药物合用有本剂。

Antipyretic effect is stronger than analgesic action. Efficacy of intensity to the role of aspirin, slow and persistent, low toxicity. Research shows that: the product and its metabolites paracetamol have antipyretic effect. Because the enzyme inhibitors which phenacetin cannot be converted to paracetamol, still can show the obvious antipyretic effect. The antipyretic effect of reason to line after product is not produced by the active products paracetamol. Mild analgesic action of phenacetin, general can last three to four hours; With the synergy of salicylic acid class share, enhance the analgesic effects. Mainly used for small animals antipyretic analgesic clinically. This product is also one of APC tablets of components.
解热作用强于镇痛作用。疗效强于阿司匹林的作用，缓慢而持久，毒性低。本品及其代谢产物扑热息痛有解热作用。由于非那西丁不能转化为扑热息痛的酶抑制剂，仍能显示出明显的解热作用。故行后产品的解热作用不是由活性产品扑热息痛产生的。非那西丁的温和镇痛作用，一般可持续三至四个小时；与水杨酸类合用，增强镇痛作用。临床上主要用于小动物解热镇痛。该产品也是APC片的组成部分之一。